課程名稱 |
生物資訊與計算分子生物學 Bioinformatics and Computational Molecular Biology |
開課學期 |
100-1 |
授課對象 |
電機資訊學院 生醫電子與資訊學研究所 |
授課教師 |
高成炎 |
課號 |
CSIE7726 |
課程識別碼 |
922 U0020 |
班次 |
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學分 |
3 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四6,7,8(13:20~16:20) |
上課地點 |
資110 |
備註 |
限學士班三年級以上 總人數上限:30人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1001bioinforamtics_k |
課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
課程大綱
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課程概述 |
Since the structure of DNA was unraveled in 1953, molecular biology has witnessed tremendous advances. With our increasing ability to manipulate bio-molecular sequences, a huge amount of data is being generated. The computer is a natural instrument for solving molecular biology problems. Computational Molecular Biology consists of the development and use of mathematical and computer science techniques in solving problems in molecular biology. |
課程目標 |
Since the structure of DNA was unraveled in 1953, molecular biology has witnessed tremendous advances. With our increasing ability to manipulate bio-molecular sequences, a huge amount of data is being generated. The computer is a natural instrument for solving molecular biology problems. Computational Molecular Biology consists of the development and use of mathematical and computer science techniques in solving problems in molecular biology. |
課程要求 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
指定閱讀 |
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參考書目 |
- 觀念生物學或高中生物課本
- 最衰者生存 |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
poster |
100% |
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|
週次 |
日期 |
單元主題 |
第1週 |
9/15 |
introduction |
第2週 |
9/22 |
next generation sequencing |
第3週 |
9/29 |
BIT2011 |
第4週 |
10/06 |
Protein Sequence and BLAST |
第5週 |
10/13 |
protein-protein interaction |
第6週 |
10/20 |
Gene Ontology and BLAST |
第7週 |
10/27 |
PPI prediction and application |
第8週 |
11/03 |
bioinformatics databases |
第9週 |
11/10 |
PPI Prediction (troubleshooting) |
第10週 |
11/17 |
siRNA, miRNA and Gene Silencing |
第11週 |
11/24 |
PROGRESS REPORT 0% |
第12週 |
12/01 |
PPI Network and Topology Analysis |
第13週 |
12/08 |
microarray and expression data |
第14週 |
12/15 |
Topology Analysis |
第15週 |
12/22 |
discussion |
第16週 |
12/29 |
discussion |
第17週 |
1/05/2012 |
poster presentation (100%) |
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